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Ribosomal Protein S6 Kinases
Hierarchy: | ∟ ∟ ∟ ∟ Ribosomal Protein S6 Kinases 43 coordinate concepts2 subordinate concepts∟ ∟ ∟ ∟ Ribosomal Protein S6 Kinases 43 coordinate concepts2 subordinate concepts∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ Ribosomal Protein S6 Kinases 43 coordinate concepts2 subordinate conceptsX |
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historyNote*: | 2003(1998); use RIBOSOMAL PROTEIN S6 KINASES (NM) 1985-1997
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publicMeSHNote*: | 2003; see RIBOSOMAL PROTEIN S6 KINASE 1998-2002; RIBOSOMAL PROTEIN S6 KINASE was indexed under PROTEIN-SERINE-THREONINE KINASES 1993-1997 & PROTEIN KINASES 1985-1992
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Scope note: | A family of protein serine/threonine kinases which act as intracellular signalling intermediates. Ribosomal protein S6 kinases are activated through phosphorylation in response to a variety of HORMONES and INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS. Phosphorylation of RIBOSOMAL PROTEIN S6 by enzymes in this class results in increased expression of 5' TOP MRNAS. Although specific for RIBOSOMAL PROTEIN S6 members of this class of kinases can act on a number of substrates within the cell. The immunosuppressant SIROLIMUS inhibits the activation of ribosomal protein S6 kinases.
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activeMeSHYear*: | |
dateCreated*: | 1997-06-20X |
dateEstablished*: | 1998-01-01X |
dateRevised*: | 2004-08-02X |
recordAuthorizer*: | jlsX |
recordMaintainer*: | jlsX |
recordOriginator*: | KEVX |
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Labels and equivalent concepts: | Ribosomaalinen proteiini S6 -kinaasit (fi) XS6-H4 Kinase (en, replaced) Ribosomal Protein S6 Kinase (en, replaced) S6 Kinase (en, replaced) Proteínas Quinasas S6 Ribosomales (es) Ribosomale Protein-S6-Kinasen (de) kinasy ribozomálního proteinu S6 (cs) Proteínas S6 Quinasas Ribosomales (es, replaced) S6 Quinasa (es, replaced) Proteínas Quinasas S6 Ribosómicas (es, replaced) S6-Kinase (de, replaced) |
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