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eIF-2 Kinase
Hierarchy: | ∟ ∟ ∟ ∟ eIF-2 Kinase 43 coordinate concepts∟ ∟ ∟ ∟ eIF-2 Kinase 43 coordinate concepts∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ eIF-2 Kinase 43 coordinate conceptsX |
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History note: | |
historyNote*: | 98; use EIF-2 KINASE (NM) 1980-97
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publicMeSHNote*: | 98; EIF-2 KINASE was indexed under PROTEIN-SERINE-THREONINE KINASES 1993-97 & PROTEIN KINASES 1980-93
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Scope note: | A dsRNA-activated cAMP-independent protein serine/threonine kinase that is induced by interferon. In the presence of dsRNA and ATP, the kinase autophosphorylates on several serine and threonine residues. The phosphorylated enzyme catalyzes the phosphorylation of the alpha subunit of EUKARYOTIC INITIATION FACTOR-2, leading to the inhibition of protein synthesis.
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activeMeSHYear*: | |
dateCreated*: | 1997-07-02X |
dateEstablished*: | 1998-01-01X |
dateRevised*: | 2005-07-08X |
recordAuthorizer*: | agsX |
recordMaintainer*: | agsX |
recordOriginator*: | KEVX |
Type: | |
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URI: | |
Labels and equivalent concepts: | EIF-2-kinaasi (fi) XP68 Protein Kinase (en, replaced) Protein Kinase PKR (en, replaced) p68 Kinase (en, replaced) p65 Kinase (en, replaced) Hemin Controlled Repressor (en, replaced) Hemin-Controlled Translational Repressor (en, replaced) Protein Kinase, RNA Activated (en, replaced) RNA-Dependent Protein Kinase (en, replaced) Self-Phosphorylating Protein Kinase (en, replaced) TIK Kinase (en, replaced) Heme-Regulated eIF-2alpha Kinase (en, replaced) Heme-Controlled Translational Repressor (en, replaced) Double Stranded RNA-Dependent eIF-2 alpha Protein Kinase (en, replaced) Double Stranded RNA-Dependent Kinase (dsl) (en, replaced) DAI Protein Kinase (en, replaced) dsRNA-Activated Inhibitor (en, replaced) DSRNA-Dep Protein Kinase (en, replaced) Heme Controlled Repressor (en, replaced) Heme-Controlled Inhibitor (en, replaced) Eukaryotic Initiation Factor 2alpha Kinase (en, replaced) eRF, eIF-2 Recycling Factor (en, replaced) eIF-2alpha Kinase (en, replaced) eIF-2 Quinasa (es) eIF-2-Kinase (de) kinasa eIF-2 (cs) Proteína Quinasa ARN-Dependente (es, replaced) Proteína Quinasa PKR (es, replaced) Proteína Quinasa Activada por ARN (es, replaced) p68 Quinasa (es, replaced) RNA-abhängige Proteinkinase (de, replaced) Proteinkinase-PKR (de, replaced) Proteinkinase, RNA-aktivierte (de, replaced) p68-Kinase (de, replaced) |
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