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Insulin-Like Growth Factor Binding Protein 1
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Broader terms: | |
Annotation: | /biosyn /drug eff /physiol /ultrastruct permitted; DF: note short X refs
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History note: | Carrier Proteins (1992-1995)X |
historyNote*: | 2005(1992)
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publicMeSHNote*: | 2005; see INSULIN-LIKE-GROWTH-FACTOR-BINDING PROTEIN-1 1996-2005; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 1 was indexed under CARRIER PROTEINS 1992-95
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Scope note: | One of the six homologous proteins that specifically bind insulin-like growth factors (SOMATOMEDINS) and modulate their mitogenic and metabolic actions. The function of this protein is not completely defined. However, several studies demonstrate that it inhibits IGF binding to cell surface receptors and thereby inhibits IGF-mediated mitogenic and cell metabolic actions. (Proc Soc Exp Biol Med 1993;204(1):4-29)
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activeMeSHYear*: | |
dateCreated*: | 1995-06-08X |
dateEstablished*: | 1996-01-01X |
dateRevised*: | 2004-07-07X |
recordAuthorizer*: | sjnX |
recordMaintainer*: | jmpX |
recordOriginator*: | TPWX |
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Labels and equivalent concepts: | Insuliininkaltaisen kasvutekijän sitojaproteiini 1 (fi) XIGFBP-1 (en, replaced) IGF-Binding Protein 1 (en, replaced) Proteína 1 de Unión a Factor de Crecimiento Similar a la Insulina (es) Insulin-Like Growth-Factor Binding Protein 1 (de) protein 1 vázající insulinu podobné růstové faktory (cs) IGFBP-1 (es, replaced) Proteína 1 de Unión a IGF (es, replaced) IGFBP-1 (de, replaced) IGF-Bindungsprotein 1 (de, replaced) |
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