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Vinca Alkaloids
Hierarchy: | ∟ ∟ ∟ ∟ ∟ Vinca Alkaloids 5 coordinate concepts4 subordinate concepts∟ ∟ ∟ ∟ ∟ ∟ Vinca Alkaloids 5 coordinate concepts4 subordinate conceptsX |
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History note: | Alkaloids (1966-1972)X |
historyNote*: | 73
X |
publicMeSHNote*: | 73
X |
Scope note: | A group of indole-indoline dimers which are ALKALOIDS obtained from the VINCA genus of plants. They inhibit polymerization of TUBULIN into MICROTUBULES thus blocking spindle formation and arresting cells in METAPHASE. They are some of the most useful ANTINEOPLASTIC AGENTS.
X |
activeMeSHYear*: | 2007X |
dateCreated*: | 1999-01-01X |
dateEstablished*: | 1973-01-01X |
dateRevised*: | 2006-07-05X |
recordAuthorizer*: | sjnX |
recordMaintainer*: | ssbX |
recordOriginator*: | NLMX |
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Labels and equivalent concepts: | Vinka-alkaloidit (fi) XAlcaloides de la Vinca (es) αλκαλοειδή βίνκας (el) Vinca-Alkaloide (de) Vinca - alkaloidy (cs) |
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