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Uroporphyrinogen III Synthetase
Hierarchy: | ∟ ∟ ∟ ∟ ∟ ∟ Uroporphyrinogen III Synthetase 11 coordinate concepts1 subordinate concept∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ |
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historyNote*: | 2005 (1975)
X |
publicMeSHNote*: | 2005; see UROPORPHYRINOGEN-III SYNTHASE 1998-2004, see UROPORPHYRINOGEN III SYNTHASE 1991-1997, see HYDRO-LYASES 1985-1990, see ISOMERASES 1975-1984
X |
Scope note: | An enzyme that catalyzes the cyclization of hydroxymethylbilane to yield UROPORPHYRINOGEN III and water. It is the fourth enzyme in the 8-enzyme biosynthetic pathway of HEME, and is encoded by UROS gene. Mutations of UROS gene result in CONGENITAL ERYTHROPOIETIC PORPHYRIA.
X |
activeMeSHYear*: | |
dateCreated*: | 1974-11-19X |
dateEstablished*: | 1991-01-01X |
dateRevised*: | 2004-10-20X |
recordAuthorizer*: | sjnX |
recordMaintainer*: | sjnX |
recordOriginator*: | NLMX |
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Labels and equivalent concepts: | Uroporfyrinogeeni-III-syntetaasi (fi) XUroporphyrinogen-III Synthase (en, replaced) Uroporphyrinogen Isomerase (en, replaced) Cosynthase (en, replaced) Uroporphyrinogen III Cosynthetase (en, replaced) Uroporfirinógeno III Sintetasa (es) ισομεράση ουροπορφυρινογόνου (el) Uroporphyrinogen-III-Synthase (de) uroporfyrinogen-III-synthetasa (cs) Cosintasa (es, replaced) Uroporfirinógeno III Cosintetasa (es, replaced) Uroporfirinógeno III Sintasa (es, replaced) Uroporfirinógeno Isomerasa (es, replaced) Uroporphyrinogen-III-Cosynthetase (de, replaced) Uroporphyrinogen-Isomerase (de, replaced) Cosynthase (de, replaced) |
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