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Picrotoxin
Hierarchy: | ∟ ∟ ∟ ∟ ∟ ∟ ∟ Picrotoxin 18 coordinate concepts∟ ∟ ∟ Picrotoxin 18 coordinate concepts∟ ∟ ∟ ∟ ∟ Picrotoxin 18 coordinate conceptsX |
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Scope note: | A noncompetitive antagonist at GABA-A receptors and thus a convulsant. Picrotoxin blocks the GAMMA-AMINOBUTYRIC ACID-activated chloride ionophore. Although it is most often used as a research tool, it has been used as a CNS stimulant and an antidote in poisoning by CNS depressants, especially the barbiturates.
X |
activeMeSHYear*: | 2007X |
dateCreated*: | 1999-01-01X |
dateRevised*: | 2006-07-05X |
recordAuthorizer*: | sjnX |
recordMaintainer*: | ssbX |
recordOriginator*: | NLMX |
Type: | |
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URI: | |
Labels and equivalent concepts: | Pikrotoksiini (fi) XPicrotoxina (es) πικροτοξίνη (el) pikrotoxin (cs) |
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