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Kernicterus
Hierarchy: | ∟ ∟ ∟ ∟ Kernicterus 10 coordinate concepts∟ ∟ ∟ ∟ Kernicterus 10 coordinate concepts∟ ∟ ∟ ∟ ∟ Kernicterus 10 coordinate concepts∟ ∟ ∟ ∟ ∟ Kernicterus 10 coordinate concepts∟ ∟ ∟ ∟ Kernicterus 10 coordinate concepts∟ ∟ ∟ ∟ ∟ Kernicterus 10 coordinate concepts∟ ∟ ∟ ∟ Kernicterus 10 coordinate concepts∟ ∟ ∟ ∟ Kernicterus 10 coordinate conceptsX |
Broader terms: | ∟ ∟ ∟ ∟ Kernicterus ∟ ∟ ∟ ∟ Kernicterus ∟ ∟ ∟ ∟ ∟ Kernicterus ∟ ∟ ∟ ∟ ∟ Kernicterus ∟ ∟ ∟ ∟ Kernicterus ∟ ∟ ∟ ∟ ∟ Kernicterus ∟ ∟ ∟ ∟ Kernicterus ∟ ∟ ∟ ∟ Kernicterus |
Scope note: | A term used pathologically to describe BILIRUBIN staining of the BASAL GANGLIA; BRAIN STEM; and CEREBELLUM and clinically to describe a syndrome associated with HYPERBILIRUBINEMIA. Clinical features include athetosis, MUSCLE SPASTICITY or hypotonia, impaired vertical gaze, and DEAFNESS. Nonconjugated bilirubin enters the brain and acts as a neurotoxin, often in association with conditions that impair the BLOOD-BRAIN BARRIER (e.g., SEPSIS). This condition occurs primarily in neonates (INFANT, NEWBORN), but may rarely occur in adults. (Menkes, Textbook of Child Neurology, 5th ed, p613)
X |
activeMeSHYear*: | 2007X |
dateCreated*: | 1999-01-01X |
dateRevised*: | 2006-07-05X |
recordAuthorizer*: | sjnX |
recordMaintainer*: | lktX |
recordOriginator*: | NLMX |
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Labels and equivalent concepts: | Kernikterus (fi) XHyperbilirubinemic Encephalopathy (en, replaced) Encephalopathy, Hyperbilirubinemic (en, replaced) Encephalopathy, Bilirubin (en, replaced) Bilirubin Encephalopathy (en, replaced) πυρηνικός ίκτερος (el) Kernikterus (de) kernikterus (cs) Encefalopatía Bilirrubínica (es, replaced) Encefalopatía Hiperbilirrubinémica (es, replaced) Hyperbilirubinämische Enzephalophatie (de, replaced) Bilirubin-Enzephalopathie (de, replaced) |
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