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Immunoglobulin Fc Fragments
Hierarchy: | ∟ ∟ ∟ ∟ ∟ ∟ ∟ Immunoglobulin Fc Fragments 2 coordinate concepts1 subordinate concept∟ ∟ ∟ ∟ ∟ ∟ ∟ Immunoglobulin Fc Fragments 2 coordinate concepts1 subordinate concept∟ ∟ ∟ ∟ ∟ ∟ ∟ Immunoglobulin Fc Fragments 2 coordinate concepts1 subordinate concept∟ ∟ ∟ ∟ ∟ ∟ ∟ Immunoglobulin Fc Fragments 2 coordinate concepts1 subordinate concept∟ ∟ ∟ ∟ ∟ ∟ ∟ Immunoglobulin Fc Fragments 2 coordinate concepts1 subordinate concept∟ ∟ ∟ ∟ ∟ ∟ ∟ Immunoglobulin Fc Fragments 2 coordinate concepts1 subordinate conceptX |
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Annotation: | DF: IG FC
X |
History note: | Immunoglobulins (1970-1972)X |
historyNote*: | 2006 (1973)
X |
publicMeSHNote*: | 2006; see IMMUNOGLOBULINS, FC 1987-2005, see IMMUNOGLOBULIN FRAGMENTS 1984-1986, see IMMUNOGLOBULINS, FC 1973-1983
X |
Scope note: | Crystallizable fragments composed of the carboxy-terminal halves of both IMMUNOGLOBULIN HEAVY CHAINS linked to each other by disulfide bonds. Fc fragments contain the carboxy-terminal parts of the heavy chain constant regions that are responsible for the effector functions of an immunoglobulin (COMPLEMENT fixation, binding to the cell membrane via FC RECEPTORS, and placental transport). This fragment can be obtained by digestion of immunoglobulins with the proteolytic enzyme PAPAIN.
X |
activeMeSHYear*: | 2007X |
dateCreated*: | 1999-01-01X |
dateEstablished*: | 1973-01-01X |
dateRevised*: | 2006-07-05X |
recordAuthorizer*: | sjnX |
recordMaintainer*: | agsX |
recordOriginator*: | NLMX |
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Labels and equivalent concepts: | Fc-osat (fi) XImmunoglobulins, Fc (en, replaced) Immunoglobulins, Fc Fragment (en, replaced) Immunoglobulin Fc Fragment (en, replaced) Fc Immunoglobulins (en, replaced) Fc Fragments (en, replaced) Fragmentos Fc de Inmunoglobulinas (es) ανοσοσφαιρίνες Fc (el) Immunglobuline, Fc- (de) imunoglobuliny - Fc fragmenty (cs) Fragmentos Fc (es, replaced) Inmunoglobulinas Fc (es, replaced) Fc-Fragmente (de, replaced) Fc-Immunglobuline (de, replaced) Fc fragmenty (cs, replaced) |
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