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Disulfiram
Hierarchy: | ∟ ∟ ∟ ∟ ∟ ∟ ∟ Disulfiram 2 coordinate concepts∟ ∟ ∟ ∟ ∟ ∟ ∟ Disulfiram 2 coordinate concepts∟ ∟ ∟ ∟ ∟ ∟ Disulfiram 2 coordinate concepts∟ ∟ ∟ ∟ ∟ ∟ Disulfiram 2 coordinate concepts∟ ∟ ∟ ∟ ∟ Disulfiram 2 coordinate concepts∟ ∟ ∟ ∟ ∟ Disulfiram 2 coordinate concepts∟ ∟ ∟ ∟ ∟ ∟ ∟ Disulfiram 2 coordinate concepts∟ ∟ ∟ ∟ ∟ ∟ Disulfiram 2 coordinate concepts∟ ∟ ∟ ∟ ∟ Disulfiram 2 coordinate concepts∟ ∟ ∟ ∟ ∟ Disulfiram 2 coordinate conceptsX |
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Scope note: | A carbamate derivative used as an alcohol deterrent. It is a relatively nontoxic substance when administered alone, but markedly alters the intermediary metabolism of alcohol. When alcohol is ingested after administration of disulfiram, blood acetaldehyde concentrations are increased, followed by flushing, systemic vasodilation, respiratory difficulties, nausea, hypotension, and other symptoms (acetaldehyde syndrome). It acts by inhibiting aldehyde dehydrogenase.
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activeMeSHYear*: | |
dateCreated*: | 1999-01-01X |
dateRevised*: | 2005-06-30X |
recordAuthorizer*: | sjnX |
recordMaintainer*: | exlX |
recordOriginator*: | NLMX |
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Labels and equivalent concepts: | Disulfiraami (fi) XSanofi Synthelabo Brand of Disulfiram (en, replaced) Orphan Brand of Disulfiram (en, replaced) Tetraethylthioperoxydicarbonic Diamide, ((H2N)C(S))2S2 (en, replaced) Tetraethylthiuram Disulfide (en, replaced) Odyssey Brand of Disulfiram (en, replaced) Dumex Brand of Disulfiram (en, replaced) Altana Pharma Brand of Disulfiram (en, replaced) Allphar Brand of Disulfiram (en, replaced) Artu Brand of Disulfiram (en, replaced) Bis(diethylthiocarbamoyl) Disulfide (en, replaced) Bohm Brand of Disulfiram (en, replaced) δισουλφιράμη (el) Disulfuro de Tetraetiltiuramo (es, replaced) Tetraethylthiuramdisulfid (de, replaced) |
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