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The way concept relations are shown:
Cisplatin
Hierarchy: | ∟ ∟ ∟ Cisplatin 14 coordinate concepts∟ ∟ ∟ Cisplatin 14 coordinate concepts∟ ∟ ∟ Cisplatin 14 coordinate conceptsX |
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History note: | |
historyNote*: | 84(81); was see under DIAMMONIUM CHLOROPLATINUM COMPOUNDS 1981-83; was PLATINUM DIAMMINODICHLORIDE see under DIAMMONIUM CHLOROPLATINUM COMPOUNDS 1974-80; DIAMMONIUM CHLOROPLATINUM COMPOUNDS was heading 1974-83
X |
onlineNote*: | use CISPLATIN to search PLATINUM DIAMMINODICHLORIDE 1974-80 & DIAMMONIUM CHLOROPLATINUM COMPOUNDS 1974-83
X |
publicMeSHNote*: | 84; was see under DIAMMONIUM CHLOROPLATINUM COMPOUNDS 1981-83; was PLATINUM DIAMMINODICHLORIDE see under DIAMMONIUM CHLOROPLATINUM COMPOUNDS 1974-80; DIAMMONIUM CHLOROPLATINUM COMPOUNDS was heading 1974-83
X |
Scope note: | An inorganic and water-soluble platinum complex. After undergoing hydrolysis, it reacts with DNA to produce both intra and interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity of cisplatin correlates with cellular arrest in the G2 phase of the cell cycle.
X |
activeMeSHYear*: | |
dateCreated*: | 1999-01-01X |
dateEstablished*: | 1984-01-01X |
dateRevised*: | 2001-07-25X |
recordAuthorizer*: | sjnX |
recordMaintainer*: | jmpX |
recordOriginator*: | NLMX |
Type: | |
Coordinate terms: | |
URI: | |
Labels and equivalent concepts: | Sisplatiini (fi) XPlatinum Diamminodichloride (en, replaced) Dichlorodiammineplatinum (en, replaced) cis-Platinum (en, replaced) cis-Dichlorodiammineplatinum(II) (en, replaced) cis-Diamminedichloroplatinum (en, replaced) cis-Diamminedichloroplatinum(II) (en, replaced) Cisplatino (es) σισπλατίνη (el) cisplatina (cs) cis-Diaminodicloroplatino (II) (es, replaced) cis-Diclorodiaminoplatino (II) (es, replaced) Diaminocloruro de Platino (es, replaced) cis-Dichlorodiamminplatin (II) (de, replaced) Platindiammindichlorid (de, replaced) cis-Diammindichloroplatin (II) (de, replaced) |
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