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The way concept relations are shown:
Cimetidine
Hierarchy: | ∟ ∟ ∟ ∟ ∟ Cimetidine 53 coordinate concepts∟ ∟ Agmatine | ∟ ∟ ∟ Creatine | ∟ Gabexate | ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ Biotin | ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ Etimizol | ∟ ∟ ∟ ∟ ∟ ∟ Idazoxan | ∟ ∟ ∟ ∟ Losartan | ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ Cimetidine 53 coordinate concepts∟ ∟ Agmatine | ∟ ∟ ∟ Creatine | ∟ Gabexate | ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ Biotin | ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ Etimizol | ∟ ∟ ∟ ∟ ∟ ∟ Idazoxan | ∟ ∟ ∟ ∟ Losartan | ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ |
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History note: | |
historyNote*: | 84(78); was see under GUANIDINES 1978-83
X |
publicMeSHNote*: | 84; was see under GUANIDINES 1978-83
X |
Scope note: | A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRINS output. It also blocks the activity of CYTOCHROME P-450 which might explain proposals for use in NEOADJUVANT THERAPY.
X |
activeMeSHYear*: | 2007X |
dateCreated*: | 1977-04-22X |
dateEstablished*: | 1984-01-01X |
dateRevised*: | 2006-07-05X |
recordAuthorizer*: | sjnX |
recordMaintainer*: | ssbX |
recordOriginator*: | SHX |
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Labels and equivalent concepts: | Simetidiini (fi) XSKF-92334 (en, replaced) N-Cyano-N'-methyl-N''-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)guanidine (en, replaced) Cimetidine HCl (en, replaced) Cimetidina (es) σιμετιδίνη (el) Cimetidin (de) cimetidin (cs) |
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